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Sometimes, people may feel tired or lethargic due to high medicine doses. I wanted to learn everything about the industry and the products out there. I tested and reviewed numerous CBD brands for efficacy, purity, and transparency, and found that very few delivered consistent relief, and many contained pesticides and heavy metals.
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Wilsey B., Marcotte T., Tsodikov A., Millman J., Bentley H., Gouaux B., Fishman S. A randomized, placebo-controlled, crossover trial of cannabis cigarettes in neuropathic pain. Munro S., Thomas K.L., Abu-Shaar M. Molecular characterization of a peripheral receptor for cannabinoids. Soares V.P., Campos A.C. Evidences for the anti-panic actions of cannabidiol. Hence, in cases of treatment resistance, novel treatment approaches, as discussed in this review, may address the risk of neuroprogression. Abundant evidence points to an elevation in inflammatory markers in affective disorders [83-86].
Sartim A. G., Guimarães F. S., Joca S. R. L. Antidepressant-like Effect of cannabidiol injection into the ventral medial prefrontal cortex-possible involvement of 5-HT1A and CB1 receptors. Shoval G., Shbiro L., Hershkovitz L., Hazut N., Zalsman G., Mechoulam R., Weller A. Prohedonic effect of cannabidiol in a rat model of depression. Morales P., Reggio P. H., Jagerovic N. An overview on medicinal chemistry of synthetic and natural derivatives of cannabidiol. Campos A.C., Fogaça M.V., Sonego A.B., Guimarães F.S. Cannabidiol, neuroprotection and neuropsychiatric disorders. Iseger T.A., Bossong M.G. A Systematic review of the antipsychotic properties of cannabidiol in humans. Cuttler C., Spradlin A., McLaughlin R. J. A Naturalistic examination of the perceived effects of cannabis on negative affect.
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